Triprolidine
Antihistamine medication
- C (US)
administration
- R06AX07 (WHO)
- US: OTC
- 2-[(E)-1-(4-methylphenyl)-3-pyrrolidin-1-yl-
prop-1-enyl]pyridine
- 486-12-4
Y
- 5282443
- 1228
- DB00427 Y
- 4445597 Y
- 2L8T9S52QM
- D01782
N
- CHEBI:84116 N
- ChEMBL855 Y
- DTXSID3023718
- Interactive image
- n3c(\C(=C\CN1CCCC1)c2ccc(cc2)C)cccc3
- InChI=1S/C19H22N2/c1-16-7-9-17(10-8-16)18(19-6-2-3-12-20-19)11-15-21-13-4-5-14-21/h2-3,6-12H,4-5,13-15H2,1H3/b18-11+Y
- Key:CBEQULMOCCWAQT-WOJGMQOQSA-NY
N
Y (what is this?) (verify)Triprolidine is an over-the-counter antihistamine with anticholinergic properties.[1] It is used to combat the symptoms associated with allergies and is sometimes combined with other cold medications designed to provide general relief for flu-like symptoms.[2] As with many antihistamines, the most common side effect is drowsiness.[1]
It was patented in 1948 and came into medical use in 1953.[3]
See also
- Benzatropine
- Pseudoephedrine
- UK-9040
References
- ^ a b Goldsmith P, Dowd PM (January 1993). "The new H1 antihistamines. Treatment of urticaria and other clinical problems". Dermatologic Clinics. 11 (1): 87–95. doi:10.1016/S0733-8635(18)30285-7. PMID 8094649.
- ^ Williams BO, Liao SH, Lai AA, Arnold JD, Perkins JG, Blum MR, Findlay JW (1984). "Bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products". Clinical Pharmacy. 3 (6): 638–43. PMID 6509877.
- ^ Fischer J, Ganellin CR (2006). Analogue-based Drug Discovery. John Wiley & Sons. p. 546. ISBN 9783527607495.
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