Isoaminile

Chemical compound

R05DB04 (WHO)

Identifiers

IUPAC name

4-(dimethylamino)-2-isopropyl-2-phenylpentanenitrile

CAS Number

77-51-0^Y

PubChem CID

6481

DrugBank

DB08944^N

ChemSpider

6236^Y

UNII

R4823W2PQL

KEGG

D08088^Y

CompTox Dashboard (EPA)

DTXSID5057830

ECHA InfoCard100.000.940

Chemical and physical dataFormulaC₁₆H₂₄N₂Molar mass244.382 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

N#CC(c1ccccc1)(C(C)C)CC(N(C)C)C

InChI

InChI=1S/C16H24N2/c1-13(2)16(12-17,11-14(3)18(4)5)15-9-7-6-8-10-15/h6-10,13-14H,11H2,1-5H3^Y
Key:WFLSCFISQHLEED-UHFFFAOYSA-N^Y

^NY (what is this?) (verify)

Isoaminile is an antitussive (cough suppressant) used under the trade-name Peracon.^[1]

The normal therapeutic dose is 40–80 mg of the cyclamate salt, with a maximum of five doses in a 24-hour period.^{[citation needed]} In addition to its central antitussive effects, it is also an anticholinergic, exhibiting both antimuscarinic and antinicotinic actions.^{[citation needed]}

References

^ Chappel CI, von Seeman C (1963). "Antitussive Drugs". In Ellis GP, West GB (eds.). Progress in Medicinal Chemistry. Vol. 3. Butterworth. pp. 114–115. doi:10.1016/S0079-6468(08)70117-6. ISBN 978-0-444-53322-7. PMID 14146305. Retrieved 2013-09-12.

Cough and cold preparations (R05)

Expectorants

Althea root
Ammonium Chloride
Antimony pentasulfide
Cineole
Creosote
Guaiacolsulfonate
Guaifenesin (+codeine, +hydrocodone, +oxomemazine)
Hederae helicis folium
Ipecacuanha (Syrup of ipecac)
Levoverbenone
Potassium iodide
Senega
Tyloxapol

Mucolytics

Cough suppressants

Opium alkaloids, opioids, and derivatives	Acetyldihydrocodeine Benzylmorphine Butorphanol Codeine^# (+guaifenesin) Dextromethorphan Dihydrocodeine Dimemorfan Ethylmorphine Heroin Hydrocodone (+guaifenesin, +homatropine) Hydromorphone Laudanum Levomethadone Levopropoxyphene Methadone Nicocodeine Nicodicodeine Normethadone Noscapine Pholcodine Thebacon
Other	Alloclamide Benproperine Benzonatate Bibenzonium bromide Butamirate Clobutinol Clofedanol Cloperastine Dibunate Dimethoxanate Diphenhydramine Dropropizine Droxypropine Fedrilate Fominoben Gefapixant Glaucine Isoaminile Levodropropizine Meprotixol Moguisteine Morclofone Nepinalone Oxeladin Oxolamine Pentoxyverine Pipazetate Piperidione Prenoxdiazine Tipepidine Zipeprol

Opium alkaloids,
opioids,
and derivatives