2,5-Dimethoxy-4-ethoxyamphetamine

IdentifiersCAS NumberPubChem CIDChemSpiderUNIIChEMBLCompTox Dashboard (EPA)Chemical and physical dataFormulaC₁₃H₂₁NO₃Molar mass239.315 g·mol⁻¹3D model (JSmol) ^NY (what is this?)  (verify)

2,5-Dimethoxy-4-ethoxyamphetamine (MEM) is a psychedelic drug of the phenethylamine and amphetamine chemical classes. It was first synthesized by Alexander Shulgin.^[1] In his book PiHKAL, he lists the active dose range as 20–50 mg, and the duration as 10–14 hours.^[1] According to Shulgin, MEM produces color enhancement, visual phenomena, and pattern movement, among other effects.^[1]

MEM possesses affinity (K_i) for the 5-HT_2A (3,948 nM), 5-HT_2B (64.5 nM), 5-HT₇ (7,156 nM), and σ₁ (5,077 nM) receptors. It behaves as a partial agonist at the 5-HT_2A receptor.^[2] MEM is relatively selective for these sites and displays low/negligible (> 10,000 nM) affinity for a wide array of other targets.^[2]

See also

• 2,5-Dimethoxy-4-substituted amphetamines

References

External links

• MEM entry in PiHKAL
• MEM entry in PiHKAL • info