Propiverine

Chemical compound

G04BD06 (WHO)

Legal statusLegal status

CA: ℞-only^[1]

Pharmacokinetic dataElimination half-life20.1 hIdentifiers

IUPAC name

1-methylpiperidin-4-yl diphenyl(propoxy)acetate

CAS Number

60569-19-9^Y
HCl: 54556-98-8^Y

PubChem CID

4942

ChemSpider

4773^N

UNII

468GE2241L
HCl: DC4GZD10H3^Y

CompTox Dashboard (EPA)

DTXSID5048265

Chemical and physical dataFormulaC₂₃H₂₉NO₃Molar mass367.489 g·mol⁻¹3D model (JSmol)

Interactive image

SMILES

CCCOC(C1=CC=CC=C1)(C2=CC=CC=C2)C(=O)OC3CCN(CC3)C

InChI

InChI=1S/C23H29NO3/c1-3-18-26-23(19-10-6-4-7-11-19,20-12-8-5-9-13-20)22(25)27-21-14-16-24(2)17-15-21/h4-13,21H,3,14-18H2,1-2H3^N
Key:QPCVHQBVMYCJOM-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

Propiverine is an anticholinergic drug used for the treatment of urinary urgency, frequency and urge incontinence, all symptoms of overactive bladder syndrome.^[2]^[3] It is a muscarinic antagonist.^[4]

References

^ "Digestive and bladder health". Health Canada. 9 May 2018. Retrieved 13 April 2024.
^ McKeage K (January 2013). "Propiverine: a review of its use in the treatment of adults and children with overactive bladder associated with idiopathic or neurogenic detrusor overactivity, and in men with lower urinary tract symptoms". Clinical Drug Investigation. 33 (1): 71–91. doi:10.1007/s40261-012-0046-9. PMID 23288694. S2CID 3399082.
^ Huang W, Zong H, Zhou X, Wang T, Zhang Y (December 2015). "Efficacy and Safety of Propiverine Hydrochloride for Overactive Bladder in Adult: a Systematic Review and Meta-analysis". The Indian Journal of Surgery. 77 (Suppl 3): 1369–1377. doi:10.1007/s12262-015-1264-1. PMC 4775592. PMID 27011567.
^ BNF 61. London: British Medical Journal Group and Pharmaceutical Press. March 2011. p. 511. ISBN 978-0-85369-962-0.