Berbamine

Berbamine
Identifiers
CAS Number
  • 478-61-5 ☒N
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL504323 ☒N
ChemSpider
  • 9764 checkY
ECHA InfoCard 100.006.840 Edit this at Wikidata
PubChem CID
  • 10170
UNII
  • V5KM4XJ0WM ☒N
CompTox Dashboard (EPA)
  • DTXSID40963943 Edit this at Wikidata
InChI
  • InChI=1S/C37H40N2O6/c1-38-14-12-24-19-32(41-3)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-31-18-23(8-11-30(31)40)17-29-35-25(13-15-39(29)2)20-34(42-4)36(43-5)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3 checkY
    Key: DFOCUWZXJBAUSQ-UHFFFAOYSA-N checkY
  • InChI=1/C37H40N2O6/c1-38-14-12-24-19-32(41-3)33-21-27(24)28(38)16-22-6-9-26(10-7-22)44-31-18-23(8-11-30(31)40)17-29-35-25(13-15-39(29)2)20-34(42-4)36(43-5)37(35)45-33/h6-11,18-21,28-29,40H,12-17H2,1-5H3
    Key: DFOCUWZXJBAUSQ-UHFFFAOYAJ
  • O(c7c(OC)cc4c5c7Oc1cc2c(cc1OC)CCN(C)C2Cc6ccc(Oc3cc(ccc3O)CC5N(C)CC4)cc6)C
Properties
Chemical formula
C37H40N2O6
Molar mass 608.7233
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)
Infobox references
Chemical compound

Berbamine is a calcium channel blocker.

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Ion channel modulators
Calcium
VDCCsTooltip Voltage-dependent calcium channels
Blockers
Activators
Potassium
VGKCsTooltip Voltage-gated potassium channels
Blockers
Activators
IRKsTooltip Inwardly rectifying potassium channel
Blockers
Activators
  • GIRKTooltip G protein-coupled inwardly rectifying potassium channel-specific: ML-297 (VU0456810)
KCaTooltip Calcium-activated potassium channel
Blockers
  • BKCa-specific: Ethanol (alcohol)
  • GAL-021
Activators
K2PsTooltip Tandem pore domain potassium channel
Blockers
Activators
Sodium
VGSCsTooltip Voltage-gated sodium channels
Blockers
Activators
ENaCTooltip Epithelial sodium channel
Blockers
Activators
  • Solnatide
ASICsTooltip Acid-sensing ion channel
Blockers
Chloride
CaCCsTooltip Calcium-activated chloride channel
Blockers
Activators
CFTRTooltip Cystic fibrosis transmembrane conductance regulator
Blockers
Activators
Unsorted
Blockers
Others
TRPsTooltip Transient receptor potential channels
  • See here instead.
LGICsTooltip Ligand gated ion channels
  • See here instead.
See also: Receptor/signaling modulators • Transient receptor potential channel modulators
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