Bencyclane
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IUPAC name 3-[(1-benzylcycloheptyl)oxy]-N,N-dimethylpropan-1-amine | |
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ECHA InfoCard | 100.016.861 |
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InChI
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Properties | |
Chemical formula | C19H31NO |
Molar mass | 289.45554 |
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C04AX11 (WHO) | |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). N verify (what is YN ?) Infobox references |
Chemical compound
Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor.[1]
Synthesis
Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol [4006-73-9] (1'). Williamson ether synthesis with 3-dimethylaminopropylchloride [109-54-6] (2) completed the synthesis of bencyclane (3).
See also
- Clofenciclan
References
- ^ J. Elks, ed. (2014). The Dictionary of Drugs: Chemical Data, Structures and Bibliographies. Springer.
- ^ Pallos, L.; Budai, Z.; Zólyomi, G. (1972). "Basic ethers of 1-substituted cycloalkanols. 1". Arzneimittel-Forschung. 22 (9): 1502–1505. PMID 4678613.
- ^ Pallos, L.; Budai, Z.; Zólyomi, G. (1972). "Basic ethers of 1-substituted cycloalkanols. 2". Arzneimittel-Forschung. 22 (9): 1505–1509. PMID 4678614.
- ^ Anon., ES 376120 (1972-04-01 to Gallardo Antonio SA).
- ^ Spaeter Genannt Werden Wird, DE 2455051A1 (1975 to Andreu S A Lab).
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Ion channel modulators
VGKCsTooltip Voltage-gated potassium channels |
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IRKsTooltip Inwardly rectifying potassium channel |
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KCaTooltip Calcium-activated potassium channel |
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K2PsTooltip Tandem pore domain potassium channel |
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VGSCsTooltip Voltage-gated sodium channels |
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ENaCTooltip Epithelial sodium channel |
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ASICsTooltip Acid-sensing ion channel |
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CaCCsTooltip Calcium-activated chloride channel |
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CFTRTooltip Cystic fibrosis transmembrane conductance regulator |
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Unsorted |
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TRPsTooltip Transient receptor potential channels |
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LGICsTooltip Ligand gated ion channels |
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See also: Receptor/signaling modulators • Transient receptor potential channel modulators
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