Orthocaine

Orthocaine
Names
Preferred IUPAC name
Methyl 3-amino-4-hydroxybenzoate
Other names
aminobenz
Identifiers
CAS Number
  • 536-25-4 checkY
3D model (JSmol)
  • Interactive image
Beilstein Reference
 3-14-00-01477
ChemSpider
  • 10358
ECHA InfoCard 100.007.845 Edit this at Wikidata
EC Number
  • 208-627-3
KEGG
  • C14171
PubChem CID
  • 10815
UNII
  • JK16YI13QK checkY
CompTox Dashboard (EPA)
  • DTXSID2060208 Edit this at Wikidata
InChI
  • InChI=1S/C8H9NO3/c1-12-8(11)5-2-3-7(10)6(9)4-5/h2-4,10H,9H2,1H3
    Key: VNQABZCSYCTZMS-UHFFFAOYSA-N
  • COC(=O)C1=CC(N)=C(O)C=C1
Properties
Chemical formula
 C8H9NO3
Molar mass 167.16196
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound

Orthocaine is a local anesthetic. Developed in the 1890s, it was found to be of limited use due to its low solubility in water, but it has been used in powdered form to dust onto painful wounds.[1][2][3]

References

  1. ^ Walter Sneader (23 June 2005). Drug Discovery: A History. John Wiley & Sons. pp. 127–9. ISBN 978-0-471-89979-2.
  2. ^ Rajbir Singh (2002). Synthetic Drugs. Mittal Publications. pp. 167–8. ISBN 978-81-7099-831-0.
  3. ^ Stanley Alstead (22 October 2013). Poulsson's Text-Book of Pharmacology and Therapeutics. Elsevier. pp. 104–5. ISBN 978-1-4832-2584-5.
  • v
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Local anesthetics (primarily sodium channel blockers) (N01B)
Esters by acid
Aminobenzoic
Benzoic
ArCO2- (not para-amino or Ph)
  • Amoproxan (3,4,5-Trimethoxybenzoyl)
  • 3-(p-Fluorobenzoyloxy)tropane
AmidesCombinations


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