SYT11 |
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Identifiers |
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Aliases | SYT11, SYT12, sytXI, synaptotagmin 11 |
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External IDs | OMIM: 608741 MGI: 1859547 HomoloGene: 23120 GeneCards: SYT11 |
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Gene location (Human) |
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| Chr. | Chromosome 1 (human)[1] |
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| Band | 1q22 | Start | 155,859,567 bp[1] |
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End | 155,885,199 bp[1] |
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Gene location (Mouse) |
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| Chr. | Chromosome 3 (mouse)[2] |
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| Band | 3 F1|3 38.96 cM | Start | 88,652,007 bp[2] |
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End | 88,682,471 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - external globus pallidus
- inferior ganglion of vagus nerve
- postcentral gyrus
- prefrontal cortex
- Brodmann area 46
- ventral tegmental area
- ganglionic eminence
- superior frontal gyrus
- Brodmann area 9
- subthalamic nucleus
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| Top expressed in | - motor neuron
- anterior horn of spinal cord
- substantia nigra
- dorsomedial hypothalamic nucleus
- ventral tegmental area
- pontine nuclei
- subiculum
- medial dorsal nucleus
- dorsal tegmental nucleus
- medial geniculate nucleus
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| More reference expression data |
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BioGPS |
| More reference expression data |
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Gene ontology |
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Molecular function | - clathrin binding
- calcium ion binding
- syntaxin binding
- protein binding
- metal ion binding
- translation initiation factor binding
- ubiquitin protein ligase binding
- SNARE binding
- protein homodimerization activity
- beta-tubulin binding
- calcium-dependent phospholipid binding
- phosphatidylserine binding
| Cellular component | - integral component of membrane
- cell junction
- synapse
- integral component of plasma membrane
- synaptic vesicle membrane
- membrane
- cytoplasmic vesicle
- vesicle
- phagocytic cup
- presynaptic active zone membrane
- inhibitory synapse
- synaptic vesicle
- presynapse
- dendritic spine
- lysosome
- cytoplasm
- recycling endosome
- postsynaptic density
- plasma membrane
- cell body
- axon
- early phagosome
- excitatory synapse
- neuron projection
- terminal bouton
- phagocytic vesicle
- perinuclear region of cytoplasm
- integral component of synaptic vesicle membrane
- Schaffer collateral - CA1 synapse
- postsynapse
- integral component of presynaptic active zone membrane
- exocytic vesicle
| Biological process | - negative regulation of neurotransmitter secretion
- regulation of phagosome maturation
- regulation of defense response to bacterium
- calcium ion-regulated exocytosis of neurotransmitter
- negative regulation of synaptic vesicle endocytosis
- negative regulation of membrane invagination
- vesicle fusion
- protein homotetramerization
- negative regulation of clathrin-dependent endocytosis
- negative regulation of phagocytosis
- positive regulation of protein localization to phagocytic vesicle
- plasma membrane repair
- response to wounding
- negative regulation of clathrin-coated pit assembly
- calcium ion regulated lysosome exocytosis
- regulation of calcium ion-dependent exocytosis
- regulation of dopamine secretion
- vesicle-mediated transport
- calcium-ion regulated exocytosis
- cellular response to calcium ion
| Sources:Amigo / QuickGO |
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Orthologs |
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Species | Human | Mouse |
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Entrez | | |
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Ensembl | | |
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UniProt | | |
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RefSeq (mRNA) | | |
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RefSeq (protein) | | |
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Location (UCSC) | Chr 1: 155.86 – 155.89 Mb | Chr 3: 88.65 – 88.68 Mb |
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PubMed search | [3] | [4] |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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