Octodrine

DMAA substitute
  • none
Legal statusLegal status
  • US: Unapproved "New Drug" (as defined by 21 U.S. Code § 321(p)(1)). Use in dietary supplements, food, or medicine is unlawful; otherwise uncontrolled.[2]
Identifiers
  • 6-methylheptan-2-amine
CAS Number
  • 543-82-8 ☒N
PubChem CID
  • 10982
ChemSpider
  • 10517
UNII
  • 3GQ9E911BI
CompTox Dashboard (EPA)
  • DTXSID8046535 Edit this at Wikidata
ECHA InfoCard100.008.047 Edit this at WikidataChemical and physical dataFormulaC8H19NMolar mass129.247 g·mol−13D model (JSmol)
  • Interactive image
  • CC(C)CCCC(C)N
InChI
  • InChI=1S/C8H19N/c1-7(2)5-4-6-8(3)9/h7-8H,4-6,9H2,1-3H3
  • Key:QNIVIMYXGGFTAK-UHFFFAOYSA-N
  (verify)

Octodrine (also known as Vaporpac or DMHA) is a stimulant drug whose pharmacology was studied in a dozen animal studies from the 1940s through the 1970s. These studies found that octodrine can increase blood pressure and cardiac output in animals. The drug was previously approved for use by the FDA as an inhalant (i.e., Vaporpac and Tickle Tackle Inhaler) and in Germany as an oral agent as part of a multicomponent medication (i.e., Ambredin and Ordinal), but is no longer available.[3]

DMHA has also been found as an adulterant in sports supplements and is sold online as a designer drug.[3] [4]

Related designer drugs

References

  1. ^ CID 10982 from PubChem
  2. ^ "DMHA in Dietary Supplements". FDA. March 6, 2023. Retrieved June 9, 2023.
  3. ^ a b Cohen PA, Travis JC, Keizers PH, Deuster P, Venhuis BJ (June 2018). "Four experimental stimulants found in sports and weight loss supplements: 2-amino-6-methylheptane (octodrine), 1,4-dimethylamylamine (1,4-DMAA), 1,3-dimethylamylamine (1,3-DMAA) and 1,3-dimethylbutylamine (1,3-DMBA)". Clinical Toxicology. 56 (6): 421–426. doi:10.1080/15563650.2017.1398328. PMID 29115866. S2CID 5193271.
  4. ^ "Designer Stimulants: What Athletes Should Know | USADA". 24 January 2019.
  • v
  • t
  • e
AdamantanesAdenosine antagonistsAlkylaminesAmpakinesArylcyclohexylaminesBenzazepinesCathinonesCholinergicsConvulsantsEugeroicsOxazolinesPhenethylamines
PhenylmorpholinesPiperazinesPiperidinesPyrrolidinesRacetamsTropanesTryptaminesOthers
  • v
  • t
  • e
DRAsTooltip Dopamine releasing agents
NRAsTooltip Norepinephrine releasing agents
SRAsTooltip Serotonin releasing agents
Others
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins
Stub icon

This drug article relating to the nervous system is a stub. You can help Wikipedia by expanding it.

  • v
  • t
  • e