6-CAT

Chemical compound
  • In general: uncontrolled
Identifiers
  • 6-Chloro-1,2,3,4-tetrahydronaphtalen-2-amine
CAS Number
  • 60480-00-4
PubChem CID
  • 16244336
ChemSpider
  • 11269876 checkY
CompTox Dashboard (EPA)
  • DTXSID20585667 Edit this at Wikidata
Chemical and physical data3D model (JSmol)
  • Interactive image
  • C1CC2=C(CC1N)C=CC(=C2)Cl
InChI
  • InChI=1S/C10H12ClN/c11-9-3-1-8-6-10(12)4-2-7(8)5-9/h1,3,5,10H,2,4,6,12H2 checkY
  • Key:CJRJTCMSQLEPFQ-UHFFFAOYSA-N checkY
  (verify)

6-Chloro-2-aminotetralin (6-CAT) is a drug which acts as a selective serotonin releasing agent (SSRA) and is a putative entactogen in humans.[1][2] It is a rigid analogue of para-chloroamphetamine (PCA).[1]

According to Nichols et al.,[3] 6-CAT is a non-neurotoxic analog of PCA.

See also

  • 2-Aminotetralin

References

  1. ^ a b Fuller RW, Perry KW, Baker JC, Molloy BB (November 1974). "6-Chloro-2-aminotetralin, a rigid Conformational analog of 4-chloroamphetamine: pharmacologic properties of it and related compounds in rats". Archives Internationales de Pharmacodynamie et de Therapie. 212 (1): 141–53. PMID 4455127.
  2. ^ Fuller RW, Wong DT, Snoddy HD, Bymaster FP (1977). "Comparison of the effects of 6-chloro-2-aminotetralin and of ORG 6582, a related chloroamphetamine analog, on brain serotonin metabolism in rats". Biochemical Pharmacology. 26 (1): 1, 333–1, 337. doi:10.1016/0006-2952(77)90094-6.
  3. ^ Johnson MP, Frescas SP, Oberlender R, Nichols DE (May 1991). "Synthesis and pharmacological examination of 1-(3-methoxy-4-methylphenyl)-2-aminopropane and 5-methoxy-6-methyl-2-aminoindan: similarities to 3,4-(methylenedioxy)methamphetamine (MDMA)". Journal of Medicinal Chemistry. 34 (5): 1662–8. doi:10.1021/jm00109a020. PMID 1674539.
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Empathogens/entactogens
Phenylalkyl-
amines
(other than
cathinones)
Cyclized phenyl-
alkylamines
CathinonesTryptaminesChemical classes
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DRAsTooltip Dopamine releasing agents
NRAsTooltip Norepinephrine releasing agents
SRAsTooltip Serotonin releasing agents
Others
See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins