Obovatol

Obovatol
Names
Preferred IUPAC name
5-(Prop-2-en-1-yl)-3-[4-(prop-2-en-1-yl)phenoxy]benzene-1,2-diol
Identifiers
CAS Number
  • 83864-78-2 ☒N
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL491809
ChemSpider
  • 91051
PubChem CID
  • 100771
CompTox Dashboard (EPA)
  • DTXSID601003992 Edit this at Wikidata
InChI
  • InChI=1S/C18H18O3/c1-3-5-13-7-9-15(10-8-13)21-17-12-14(6-4-2)11-16(19)18(17)20/h3-4,7-12,19-20H,1-2,5-6H2
    Key: OPGPFZQBCIAFLI-UHFFFAOYSA-N
  • C=CCC1=CC=C(C=C1)OC2=CC(=CC(=C2O)O)CC=C
Properties
Chemical formula
C18H18O3
Molar mass 282.339 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound

Obovatol is a biphenolic anti-inflammatory, anxiolytic, and nootropic isolated from the bark of Magnolia obovata.[1] It is a biphenyl lignan.[2]

References

  1. ^ Choi, DY; Lee, JW; Peng, J; Lee, YJ; Han, JY; Lee, YH; Choi, IS; Han, SB; Jung, JK; Lee, WS; Lee, SH; Kwon, BM; Oh, KW; Hong, JT (2012). "Obovatol improves cognitive functions in animal models for Alzheimer's disease". Journal of Neurochemistry. 120 (6): 1048–59. doi:10.1111/j.1471-4159.2011.07642.x. PMID 22212065. S2CID 25896721.
  2. ^ Obovatol and obovatal, novel biphenyl ether lignans from the leaves of Magnolia obovata Thunb. K Ito, T Iida, K Ichino, M Tsunezuka and M Hattori, … and Pharmaceutical Bulletin, 1982
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GABAA receptor positive modulators
AlcoholsBarbituratesBenzodiazepines
CarbamatesFlavonoidsImidazolesKava constituents
  • 10-Methoxyyangonin
  • 11-Methoxyyangonin
  • 11-Hydroxyyangonin
  • Desmethoxyyangonin
  • 11-Methoxy-12-hydroxydehydrokavain
  • 7,8-Dihydroyangonin
  • Kavain
  • 5-Hydroxykavain
  • 5,6-Dihydroyangonin
  • 7,8-Dihydrokavain
  • 5,6,7,8-Tetrahydroyangonin
  • 5,6-Dehydromethysticin
  • Methysticin
  • 7,8-Dihydromethysticin
  • Yangonin
MonoureidesNeuroactive steroidsNonbenzodiazepinesPhenolsPiperidinedionesPyrazolopyridinesQuinazolinonesVolatiles/gasesOthers/unsorted
  • Unsorted benzodiazepine site positive modulators: α-Pinene
  • MRK-409 (MK-0343)
  • TCS-1105
  • TCS-1205
See also: Receptor/signaling modulators • GABA receptor modulators • GABA metabolism/transport modulators
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Types of lignans
Lignans
Lignan glycosides
Mammalian lignans (enterolignans)
Neolignans
Flavonolignans
  • Cinchonain-Ib
  • Dehydrosilybin
  • Deoxysilycistin
  • Deoxysilydianin
  • Hydnocarpin
  • Hydnowightin
  • Neosilyhermin
  • Palstatin
  • Rhodiolin
  • Salcolin A
  • Salcolin B
  • Scutellaprostin A, B, C, D, E and F
  • Silandrin
  • Silyamandin
  • Silibinin
  • Silybinome
  • Silicristin
  • Silydianin
  • Silyhermin
  • Tricin 4'-O-(erythro-beta-guaiacylglyceryl) ether
  • Tricin 4'-O-(threo-beta-guaiacylglyceryl) ether


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