Interleukin-11 receptor

Type I cytokine receptor
interleukin 11 receptor, alpha
Identifiers
SymbolIL11RA
NCBI gene3590
HGNC5967
OMIM600939
RefSeqNM_004512
UniProtQ14626
Other data
LocusChr. 9 p13
Search for
StructuresSwiss-model
DomainsInterPro
interleukin 11 receptor, beta
Identifiers
SymbolIL11RB
HGNC5968

The interleukin 11 receptor is a type I cytokine receptor, binding interleukin 11. It is a heterodimer composed of an interleukin 11 receptor alpha subunit and an incompletely characterized beta subunit.[1]

References

  1. ^ Chérel M, Sorel M, Lebeau B, Dubois S, Moreau JF, Bataille R, Minvielle S, Jacques Y (1995). "Molecular cloning of two isoforms of a receptor for the human hematopoietic cytokine interleukin-11". Blood. 86 (7): 2534–40. doi:10.1182/blood.V86.7.2534.bloodjournal8672534 (inactive 2024-04-02). PMID 7670098.{{cite journal}}: CS1 maint: DOI inactive as of April 2024 (link)

External links

  • Receptors,+Interleukin-11 at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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Cytokine receptors
Chemokine receptor
(GPCRs)
CC
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TNF receptor
1-10
11-20
21-27
JAK-STAT
Type I
γ-chain
β-chain
gp130
IL12RB1
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Type II
Ig superfamilyIL 17 familyEnzyme-linked receptor
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IL-1
IL-2
IL-3
IL-4
IL-5
  • Antagonists: YM-90709
  • Antisense oligonucleotides: TPI ASM8
IL-6
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IL-8
  • See CXCR1 (IL-8Rα) and CXCR2 (IL-8Rβ) here instead.
IL-9
  • Antibodies: Enokizumab
IL-10
IL-11
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IL-13
IL-15
IL-17
IL-18
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  • Antibodies: NNC0114-0005
  • NNC0114-0006
IL-22
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IL-31
IL1RL1
IL1RL2
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JAK
  • See here instead.
Others


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