List of corticosteroid cyclic ketals
Triamcinolone acetonide
Triamcinolone
Comparison of a corticosteroid (bottom) and its cyclic ketal derivative (top).
This is a list of corticosteroid cyclic ketals, including cyclic ketals (cyclic acetals) of steroidal glucocorticoids and mineralocorticoids. They are almost all C16α,17α cyclic ketals of corticosteroids. One of the most widely used corticosteroid cyclic ketals is triamcinolone acetonide, which is the C16α,17α acetonide (cyclic ketone with acetone) of triamcinolone.[1]
This list mostly does not include esters of corticosteroid cyclic ketals, which are listed here instead.
Acetonides
Acetonides (cyclic ketals with acetone):
- Cicortonide
- Ciprocinonide (fluocinolone acetonide cyclopropylcarboxylate)
- Descinolone acetonide (desoxytriamcinolone acetonide)
- Desonide (desfluorotriamcinolone acetonide)
- Drocinonide
- Fluclorolone acetonide (flucloronide)
- Fludroxycortide (flurandrenolide, flurandrenolone)
- Flumoxonide
- Flunisolide
- Fluocinolone acetonide
- Fluocinonide (fluocinolone acetonide 21-acetate)
- Flupamesone (triamcinolone acetonide metembonate)
- Formocortal
- Halcinonide
- Procinonide (fluocinolone acetonide propionate)
- Tralonide
- Triamcinolone acetonide
- Triamcinolone benetonide (triamcinolone acetonide 21-(benzoyl-β-aminoisobutyrate))
- Triamcinolone furetonide (triamcinolone acetonide 21-(2-benzofurancarboxylate))
- Triamcinolone hexacetonide (triamcinolone acetonide 21-tebutate)
- Triclonide
Others
Acetophenides
Acetophenides (cyclic ketals with acetophenone):
- Algestone acetophenide (dihydroxyprogesterone acetophenide)
- Amcinafide (triamcinolone acetophenide)
Acroleinides
Acroleinides (cyclic ketals with acrolein):
- Acrocinonide (triamcinolone acroleinide)
Aminobenzals
Aminobenzals (cyclic ketals with 4-dimethylaminobenzylidene):
Cyclopentanonides
Cyclopentanonides (cyclic ketals with cyclopentanone):
- Amcinonide (triamcinolone acetate cyclopentanonide)
Pentanonides
Pentanonides (cyclic ketals with 3-pentanone)
- Amcinafal (triamcinolone pentanonide)
With butyraldehyde
Cyclic ketals with butyraldehyde:
Miscellaneous
- Nicocortonide is a C14α,17α cyclic ketal with crotonaldehyde
See also
References
- ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1228–. ISBN 978-1-4757-2085-3.
- v
- t
- e
- Antagonists: Aglepristone
- Ketoconazole
- Mifepristone
- Ulipristal acetate
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
- See also
- Glucocorticoid receptor modulators
- Mineralocorticoids and antimineralocorticoids
- List of corticosteroids
