Fluocortin

Chemical compound
  • D07AB04 (WHO)
Pharmacokinetic dataBioavailability80% i.v.Elimination half-life1.3 hr.Identifiers
  • 2-[(6S,8S,9S,10R,11S,13S,14S,16R,17S)-6-Fluoro-11-hydroxy-10,13,16-trimethyl-3-oxo-6,7,8,9,11,12,14,15,16,17-decahydrocyclopenta[a]phenanthren-17-yl]-2-oxoacetic acid
CAS Number
  • 33124-50-4 checkY
PubChem CID
  • 22875828
ChemSpider
  • 18865233
UNII
  • 03837V0H1Y
KEGG
  • D07972 checkY
CompTox Dashboard (EPA)
  • DTXSID30186785 Edit this at Wikidata
ECHA InfoCard100.046.698 Edit this at WikidataChemical and physical dataFormulaC22H27FO5Molar mass390.451 g·mol−13D model (JSmol)
  • Interactive image
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InChI
  • InChI=1S/C22H27FO5/c1-10-6-13-12-8-15(23)14-7-11(24)4-5-21(14,2)18(12)16(25)9-22(13,3)17(10)19(26)20(27)28/h4-5,7,10,12-13,15-18,25H,6,8-9H2,1-3H3,(H,27,28)/t10-,12+,13+,15+,16+,17-,18-,21+,22+/m1/s1
  • Key:PUWHHWCHAVXSIG-NCLPIGKXSA-N
  (verify)

Fluocortin is a corticosteroid. It is similar to fluocortolone, but with one more keto group.[1]

References

  1. ^ Täuber U, Haack D, Nieuweboer B, Kloss G, Vecsei P, Wendt H (January 1984). "The pharmacokinetics of fluocortolone and prednisolone after intravenous and oral administration". International Journal of Clinical Pharmacology, Therapy, and Toxicology. 22 (1): 48–55. PMID 6698661.
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Glucocorticoids and antiglucocorticoids (D07, H02)
Glucocorticoids
Natural
Synthetic
AntiglucocorticoidsSynthesis modifiers
See also
Glucocorticoid receptor modulators
Mineralocorticoids and antimineralocorticoids
List of corticosteroids
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GRTooltip Glucocorticoid receptor
Agonists
  • Nonsteroidal glucocorticoids: AZD-5423
  • GSK-9027
Mixed
(SEGRMsTooltip Selective glucocorticoid receptor agonists)
Antagonists
Others
  • Antisense oligonucleotides: IONIS-GCCRRx (ISIS-426115)
See also
Receptor/signaling modulators
Glucocorticoids and antiglucocorticoids
Mineralocorticoid receptor modulators
List of corticosteroids
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