Nivacortol
Chemical compound
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| Other names | Nivazol; Nivazole; WIN-27914; Novozola; NEBO-174; 2'-(4-Fluorophenyl)-2'-H-pregna-2,4-dien-20-yno(3,2-c)pyrazol-17-ol |
| Drug class | Corticosteroid; Glucocorticoid |
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| ECHA InfoCard | 100.041.987  |
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| Formula | C28H31FN2O |
| Molar mass | 430.567 g·mol−1 |
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Nivacortol (developmental code names WIN-27914 and NEBO-174; also known as nivazol and nivazole) is a synthetic glucocorticoid corticosteroid which was never marketed.[1][2][3][4]
References
- ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 881–882. ISBN 978-1-4757-2085-3.
- ^ "Nivazole". AdisInsight. Springer Nature Switzerland AG.
- ^ Elguero J, Silva AM, Tome AC (2011). "Five-Membered Heterocycles: 1,2-Azoles, Part 1. Pyrazoles". In Alvarez-Builla J, Vaquero JJ, Barluenga J (eds.). Modern Heterocyclic Chemistry. Vol. 1. John Wiley & Sons. pp. 649–. ISBN 978-3-527-33201-4.
- ^ Honour JW, Sudan HL, Lovell G (August 1986). "The determination of nivacortol in plasma using HPLC". Biomedical Chromatography. 1 (4): 151–154. doi:10.1002/bmc.1130010404. PMID 3506827.
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Glucocorticoid receptor modulators
- See also
- Receptor/signaling modulators
- Glucocorticoids and antiglucocorticoids
- Mineralocorticoid receptor modulators
- List of corticosteroids
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