Tisopurine
Chemical compound
- M04AA02 (WHO)
- 1,2-Dihydro-4H-pyrazolo[3,4-d]pyrimidine-4-thione
- 5334-23-6
Y
- 667510
- 580886
- 79F9I2R16M
- D07278 Y
- DTXSID90201488
- Interactive image
- c1c2c([nH]n1)ncnc2S
InChI
- InChI=1S/C5H4N4S/c10-5-3-1-8-9-4(3)6-2-7-5/h1-2H,(H2,6,7,8,9,10)
- Key:PYAOPMWCFSVFOT-UHFFFAOYSA-N
Tisopurine (or thiopurinol) is a drug used in the treatment of gout in some countries.[1] It reduces uric acid production through inhibiting an early stage in its production.[2]
References
- ^ Dean BM, Perrett D, Simmonds HA, Grahame R (April 1974). "Thiopurinol: comparative enzyme inhibition and protein binding studies with allopurinol, oxipurinol and 6-mercaptopurine". British Journal of Clinical Pharmacology. 1 (2): 119–27. doi:10.1111/j.1365-2125.1974.tb00220.x. PMC 1402452. PMID 22454898.
- ^ Jawad AS (June 1987). "Alternatives to allopurinol". Annals of the Rheumatic Diseases. 46 (6): 493. doi:10.1136/ard.46.6.493-a. PMC 1002174. PMID 3632073.
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Drugs used for gout (M04)
| primary |
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| secondary |
| purine analogues |
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| other |
- #WHO-EM
- ‡Withdrawn from market
- Clinical trials:
- †Phase III
- §Never to phase III
 | This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it. |
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