Cytidine triphosphate
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IUPAC name Cytidine 5′-(tetrahydrogen triphosphate) | |
Systematic IUPAC name O1-{[(2R,3S,4R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxyoxolan-2-yl]methyl} tetrahydrogen triphosphate | |
Other names CTP; Cytidine-5'-triphosphate | |
Identifiers | |
CAS Number |
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3D model (JSmol) |
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ChemSpider |
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ECHA InfoCard | 100.000.556 |
IUPHAR/BPS |
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MeSH | Cytidine+triphosphate |
PubChem CID |
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UNII |
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CompTox Dashboard (EPA) |
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InChI
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Properties | |
Chemical formula | C9H16N3O14P3 |
Molar mass | 483.156 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). Y verify (what is YN ?) Infobox references |
Cytidine triphosphate (CTP) is a pyrimidine nucleoside triphosphate. CTP, much like ATP, consists of a ribose sugar, and three phosphate groups. The major difference between the two molecules is the base used, which in CTP is cytosine.
CTP is a substrate in the synthesis of RNA.
CTP is a high-energy molecule similar to ATP, but its role as an energy coupler is limited to a much smaller subset of metabolic reactions. CTP is a coenzyme in metabolic reactions like the synthesis of glycerophospholipids, where it is used for activation and transfer of diacylglycerol and lipid head groups,[1] and glycosylation of proteins.
CTP acts as an inhibitor of the enzyme aspartate carbamoyltransferase, which is used in pyrimidine biosynthesis.[2]
See also
References
- v
- t
- e
- Purine
- Pyrimidine
- Unnatural base pair (UBP)
Ribonucleoside |
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Deoxyribonucleoside |
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(Nucleoside monophosphate)
Ribonucleotide | |
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Deoxyribonucleotide | |
Cyclic nucleotide |