Tioclomarol

Chemical compound
  • B01AA11 (WHO)
Identifiers
  • 3-[3-(4-Chlorophenyl)-1-(5-chloro-2-thienyl)-3-hydroxypropyl]-2-hydroxy-4H-chromen-4-one
CAS Number
  • 22619-35-8
PubChem CID
  • 72147
ChemSpider
  • 11236578
UNII
  • E5B7C16LFK
KEGG
  • D07137 checkY
ChEMBL
  • ChEMBL2105401
CompTox Dashboard (EPA)
  • DTXSID80875354 Edit this at Wikidata
Chemical and physical dataFormulaC22H16Cl2O4SMolar mass447.33 g·mol−13D model (JSmol)
  • Interactive image
  • c1ccc2c(c1)c(c(c(=O)o2)C(CC(c3ccc(cc3)Cl)O)c4ccc(s4)Cl)O
InChI
  • InChI=1S/C22H16Cl2O4S/c23-13-7-5-12(6-8-13)16(25)11-15(18-9-10-19(24)29-18)20-21(26)14-3-1-2-4-17(14)28-22(20)27/h1-10,15-16,25-26H,11H2
  • Key:WRGOVNKNTPWHLZ-UHFFFAOYSA-N
  (verify)

Tioclomarol is an anticoagulant of the 4-hydroxycoumarin vitamin K antagonist type. It is a second generation drug, used as a rodenticide that is effective for the control of rodents that are resistant to this class of drugs.

References

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Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)
Antiplatelet drugs
Glycoprotein IIb/IIIa inhibitors
ADP receptor/P2Y12 inhibitors
Prostaglandin analogue (PGI2)
COX inhibitors
Thromboxane inhibitors
Phosphodiesterase inhibitors
Other
Anticoagulants
Vitamin K antagonists
(inhibit II, VII, IX, X)
Factor Xa inhibitors
(with some II inhibition)
Heparin group/
glycosaminoglycans/
(bind antithrombin)
Direct Xa inhibitors ("xabans")
Direct thrombin (IIa) inhibitors
Other
Thrombolytic drugs/
fibrinolyticsNon-medicinal
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