Ampiroxicam
Chemical compound
- none
- In general: ℞ (Prescription only)
- (RS)-Ethyl 1-[2-methyl-1,1-dioxo-3-(pyridin-2-ylcarbamoyl)benzo[e]thiazin-4-yl]oxyethyl carbonate
- 99464-64-9
Y
- 2176
- 2091 Y
- 0PV32JZB1J
- D01397 Y
- CHEBI:31210
N
- ChEMBL1909052 N
- DTXSID6046474
- Interactive image
- CCOC(=O)OC(C)OC1=C(N(S(=O)(=O)C2=CC=CC=C21)C)C(=O)NC3=CC=CC=N3
InChI
- InChI=1S/C20H21N3O7S/c1-4-28-20(25)30-13(2)29-18-14-9-5-6-10-15(14)31(26,27)23(3)17(18)19(24)22-16-11-7-8-12-21-16/h5-13H,4H2,1-3H3,(H,21,22,24)Y
- Key:LSNWBKACGXCGAJ-UHFFFAOYSA-NY
N
Y (what is this?) (verify)Ampiroxicam (INN) is a non-steroidal anti-inflammatory drug (NSAID). It is a prodrug of piroxicam.[1] It has been studied for potential anticancer activity, but preliminary results did not show evidence of such activity.[2][3]
References
- ^ Carty TJ, Marfat A, Moore PF, Falkner FC, Twomey TM, Weissman A (July 1993). "Ampiroxicam, an anti-inflammatory agent which is a prodrug of piroxicam". Agents and Actions. 39 (3–4): 157–165. doi:10.1007/BF01998969. PMID 8304243. S2CID 24284281.
- ^ Choi KH, Shim JH, Huong LD, Cho NP, Cho SD (July 2011). "Inhibition of myeloid cell leukemia-1 by tolfenamic acid induces apoptosis in mucoepidermoid carcinoma". Oral Diseases. 17 (5): 469–475. doi:10.1111/j.1601-0825.2010.01774.x. PMID 21496182.
- ^ Shim JH, Shin JA, Jung JY, Choi KH, Choi ES, Cho NP, et al. (March 2011). "Chemopreventive effect of tolfenamic acid on KB human cervical cancer cells and tumor xenograft by downregulating specificity protein 1". European Journal of Cancer Prevention. 20 (2): 102–111. doi:10.1097/CEJ.0b013e328341e38f. PMID 21131823.
- v
- t
- e
pyrazolidines
and related substances
derivatives (profens)
- Alminoprofen
- Benoxaprofen†
- Carprofen‡
- Dexibuprofen
- Dexketoprofen
- Fenbufen
- Fenoprofen
- Flunoxaprofen
- Flurbiprofen
- Ibuprofen#
- Ibuproxam
- Indoprofen†
- Ketoprofen
- Loxoprofen
- Miroprofen
- Naproxen
- Oxaprozin
- Pelubiprofen
- Piketoprofen
- Pirprofen
- Suprofen
- Tarenflurbil
- Tepoxalin‡
- Tiaprofenic acid
- Vedaprofen‡
- Zaltoprofen
- COX-inhibiting nitric oxide donator: Naproxcinod
acids (fenamates)
(coxibs)
combinations
Key: underline indicates initially developed first-in-class compound of specific group; #WHO-Essential Medicines; †withdrawn drugs; ‡veterinary use.
category
commons
portal
 | This drug article relating to the musculoskeletal system is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
 | This analgesic-related article is a stub. You can help Wikipedia by expanding it. |
- v
- t
- e
