Working Formulation
The Working Formulation is a classification of non-Hodgkin lymphomas, first proposed in 1982.[1] It has become outdated in light of modern shifts in the understanding and classification of non-Hodgkin lymphomas, leading to the rise of new systems such as the Revised American European Lymphoma classification.[2] The Working Formulation is still in use, although it is usually applied when analyzing historical data.[3]
Low Grade
- Malignant lymphoma, small lymphocytic (chronic lymphocytic leukemia)
- Malignant lymphoma, follicular, predominantly small cleaved cell
- Malignant lymphoma, follicular, mixed (small cleaved and large cell)
Intermediate grade
- Malignant lymphoma, follicular, predominantly large cell
- Malignant lymphoma, diffuse, small cleaved cell
- Malignant lymphoma, diffuse, mixed small and large cell
- Malignant lymphoma, diffuse, large cell
High grade
- Malignant lymphoma, large cell, immunoblastic
- Malignant lymphoma, lymphoblastic
- Malignant lymphoma, small noncleaved cells (Burkitt lymphoma)
Miscellaneous
- Composite
- Mycosis fungoides
- Histiocytic
- Extramedullary plasmacytoma
- Unclassifiable
References
- ^ MacKenzie RG, Rusthoven JJ (1985). "Management of localized non-Hodgkin's lymphoma". CMAJ. 133 (6): 559–64. PMC 1346220. PMID 3896450.
- ^ "Non-Hodgkin Lymphoma Treatment (PDQ®) - NCI". www.cancer.gov. 2023-12-15. Retrieved 2024-01-22.
- ^ "Non-Hodgkin Lymphoma Guidelines: Classification, Diagnosis, Staging". 2023-07-24.
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