TSPAN14

Protein-coding gene in humans
TSPAN14
Identifiers
AliasesTSPAN14, DC-TM4F2, TM4SF14, tetraspanin 14
External IDsMGI: 1196325; HomoloGene: 23717; GeneCards: TSPAN14; OMA:TSPAN14 - orthologs
Gene location (Human)
Chromosome 10 (human)
Chr.Chromosome 10 (human)[1]
Chromosome 10 (human)
Genomic location for TSPAN14
Genomic location for TSPAN14
Band10q23.1Start80,454,166 bp[1]
End80,533,124 bp[1]
Gene location (Mouse)
Chromosome 14 (mouse)
Chr.Chromosome 14 (mouse)[2]
Chromosome 14 (mouse)
Genomic location for TSPAN14
Genomic location for TSPAN14
Band14 B|14 22.36 cMStart40,628,402 bp[2]
End40,688,764 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lung

  • granulocyte

  • tibial nerve

  • upper lobe of left lung

  • monocyte

  • subcutaneous adipose tissue

  • skin of leg

  • skin of abdomen

  • apex of heart

  • ganglionic eminence
Top expressed in
  • decidua

  • primary oocyte

  • granulocyte

  • gastrula

  • stroma of bone marrow

  • transitional epithelium of urinary bladder

  • secondary oocyte

  • lens

  • right kidney

  • molar
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • enzyme binding
Cellular component
  • integral component of membrane
  • integral component of plasma membrane
  • membrane
  • plasma membrane
  • specific granule membrane
  • tertiary granule membrane
  • cell surface
  • tetraspanin-enriched microdomain
  • endoplasmic reticulum lumen
Biological process
  • positive regulation of Notch signaling pathway
  • neutrophil degranulation
  • protein localization to plasma membrane
  • protein maturation
  • cell surface receptor signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

81619

52588

Ensembl

ENSG00000108219

ENSMUSG00000037824

UniProt

Q8NG11

Q8QZY6

RefSeq (mRNA)
NM_001128309
NM_030927
NM_001351266
NM_001351267
NM_001351268

NM_001351269
NM_001351270
NM_001351271
NM_001351272

NM_145928
NM_001316748

RefSeq (protein)
NP_001121781
NP_112189
NP_001338195
NP_001338196
NP_001338197

NP_001338198
NP_001338199
NP_001338200
NP_001338201

NP_001303677
NP_666040

Location (UCSC)Chr 10: 80.45 – 80.53 MbChr 14: 40.63 – 40.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Tetraspanin 14 is a protein that in humans is encoded by the TSPAN14 gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000108219 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000037824 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: Tetraspanin 14". Retrieved 2018-10-14.

Further reading

  • Bankovic J, Stojsic J, Jovanovic D, Andjelkovic T, Milinkovic V, Ruzdijic S, Tanic N (February 2010). "Identification of genes associated with non-small-cell lung cancer promotion and progression". Lung Cancer. 67 (2): 151–9. doi:10.1016/j.lungcan.2009.04.010. PMID 19473719.


  • v
  • t
  • e