PRPF40B

Protein-coding gene in the species Homo sapiens
PRPF40B
Identifiers
AliasesPRPF40B, HYPC, pre-mRNA processing factor 40 homolog B
External IDsMGI: 1925583; HomoloGene: 81828; GeneCards: PRPF40B; OMA:PRPF40B - orthologs
Gene location (Human)
Chromosome 12 (human)
Chr.Chromosome 12 (human)[1]
Chromosome 12 (human)
Genomic location for PRPF40B
Genomic location for PRPF40B
Band12q13.12Start49,568,218 bp[1]
End49,644,666 bp[1]
Gene location (Mouse)
Chromosome 15 (mouse)
Chr.Chromosome 15 (mouse)[2]
Chromosome 15 (mouse)
Genomic location for PRPF40B
Genomic location for PRPF40B
Band15|15 F1Start99,295,087 bp[2]
End99,317,018 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • anterior pituitary

  • left testis

  • sural nerve

  • right testis

  • left ovary

  • right uterine tube

  • right ovary

  • canal of the cervix
Top expressed in
  • neural layer of retina

  • primary visual cortex

  • ventricular zone

  • superior frontal gyrus

  • genital tubercle

  • tail of embryo

  • dentate gyrus of hippocampal formation granule cell

  • spermatocyte

  • muscle of thigh

  • cerebellar cortex
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • RNA binding
Cellular component
  • U1 snRNP
  • nuclear speck
  • U2-type prespliceosome
  • nucleus
Biological process
  • mRNA splicing, via spliceosome
  • mRNA processing
  • RNA splicing
  • mRNA cis splicing, via spliceosome
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

25766

54614

Ensembl

ENSG00000110844

ENSMUSG00000023007

UniProt

Q6NWY9

Q80W14

RefSeq (mRNA)
NM_001031698
NM_012272
NM_001363607
NM_001379030
NM_001379031

NM_001379032
NM_001379033
NM_001379034
NM_001379035
NM_001379036
NM_001379037

NM_018786
NM_001348256

RefSeq (protein)
NP_001026868
NP_036404
NP_001350536
NP_001365959
NP_001365960

NP_001365961
NP_001365962
NP_001365963
NP_001365964
NP_001365965
NP_001365966

NP_061256
NP_001335185
NP_001357561
NP_001357562
NP_001357563

NP_001357564

Location (UCSC)Chr 12: 49.57 – 49.64 MbChr 15: 99.3 – 99.32 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Pre-mRNA-processing factor 40 homolog B is a protein that in humans that is encoded by the PRPF40B gene. [5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000110844 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000023007 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: PRP40 pre-mRNA processing factor 40 homolog B (S. cerevisiae)". Retrieved 2012-04-15.

Further reading

  • Buschdorf JP, Strätling WH (Feb 2004). "A WW domain binding region in methyl-CpG-binding protein MeCP2: impact on Rett syndrome". Journal of Molecular Medicine. 82 (2): 135–43. doi:10.1007/s00109-003-0497-9. PMID 14618241. S2CID 9685491.
  • Faber PW, Barnes GT, Srinidhi J, Chen J, Gusella JF, MacDonald ME (Sep 1998). "Huntingtin interacts with a family of WW domain proteins". Human Molecular Genetics. 7 (9): 1463–74. doi:10.1093/hmg/7.9.1463. PMID 9700202.


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