Dichlorophen

Chemical compound

P02DX02 (WHO)

Identifiers

IUPAC name

4-Chloro-2-[(5-chloro-2-hydroxyphenyl)methyl]phenol

CAS Number

97-23-4^Y

PubChem CID

3037

ChemSpider

2929^N

UNII

T1J0JOU64O

KEGG

C14292^Y

ChEMBL

ChEMBL33845^N

CompTox Dashboard (EPA)

DTXSID6021824

ECHA InfoCard100.002.335

Chemical and physical dataFormulaC₁₃H₁₀Cl₂O₂Molar mass269.12 g·mol⁻¹3D model (JSmol)

Interactive image

Density1.5 g/cm³ g/cm³Melting point177.5 °C (351.5 °F)Solubility in water0.003 g/100 mL^[1] mg/mL (20 °C)

SMILES

C1=CC(=C(C=C1Cl)CC2=C(C=CC(=C2)Cl)O)O

InChI

InChI=1S/C13H10Cl2O2/c14-10-1-3-12(16)8(6-10)5-9-7-11(15)2-4-13(9)17/h1-4,6-7,16-17H,5H2^N
Key:MDNWOSOZYLHTCG-UHFFFAOYSA-N^N

^NY (what is this?) (verify)

Dichlorophen is an anticestodal agent, fungicide, germicide, and antimicrobial agent.^[2] It is used in combination with toluene for the removal of parasites such as ascarids, hookworms, and tapeworms from dogs and cats.^[3]

Safety and regulation

LD50 (oral, mouse) is 3300 mg/kg.^[4]

References

^ Lide DR (1998). Handbook of Chemistry and Physics (87 ed.). Boca Raton, Florida: CRC Press. pp. 8–118. ISBN 0-8493-0594-2.
^ Milne, G.W.A. (Ed.). (2005). Gardner's commercially important chemicals: Synonyms, trade names, and properties. Hoboken, N.J.: Wiley-Interscience. Google Books
^ "Code of Federal Regulations", Code of Federal Regulations, Title 21, Volume 6, U.S. Government Printing Office, 2005-04-01, retrieved 2009-05-01
^ Fiege H, Voges HW, Hamamoto T, Umemura S, Iwata T, Miki H, Fujita Y, Buysch HJ, Garbe D, Paulus W (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313. ISBN 978-3527306732.

Antiparasitics – Anthelmintics (P02) and endectocides (QP54)

Antiplatyhelmintic agents

Antitrematodals
(schistosomicides)

Binds tubulin	benzimidazole Triclabendazole^#
AChE inhibitor	phosphonic acid Metrifonate^‡
Other/unknown	quinoline Arpraziquantel Praziquantel^# Oxamniquine^# phenol Bithionol thiazole Niridazole thioxanthone Hycanthone Lucanthone antimony compounds Stibophen Tartar emetic^‡

Anticestodals
(taeniacides)

Binds tubulin	benzimidazole Albendazole^#
Other/unknown	quinoline Praziquantel^# salicylanilide Niclosamide^# aminoacridine Quinacrine butyrophenone Desaspidin chlorophenol Dichlorophen

Antinematodal agents
(including
macrofilaricides)

Binds tubulin	benzimidazole Mebendazole^# Albendazole^# Tiabendazole Fenbendazole Ciclobendazole Flubendazole
Glutamate-gated chloride channel, GABA receptor	avermectins Abamectin Doramectin Emamectin Eprinomectin Ivermectin^# Selamectin milbemycins Moxidectin Milbemycin oxime
NMDA	tetrahydropyrimidine Pyrantel^# pyrantel pamoate Oxantel Morantel Carbantel Febantel (aka felsantel)
Other/unknown	piperazine Piperazine Diethylcarbamazine^# thiazole Levamisole^# quinolinium Pyrvinium benzylammonium Bephenium naphthalenesulfonate Suramin^# Ascaridole^‡ Hexylresorcinol Santonin^‡ Tribendimidine Tetrachloroethylene^‡