Dialysis adequacy
Measurement of renal dialysis
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| Purpose | the measurement of renal dialysis |
In nephrology, dialysis adequacy is the measurement of renal dialysis for the purpose of determining dialysis treatment regime and to better understand the pathophysiology of renal dialysis.[1] It is an area of considerable controversy in nephrology.[2]
In the US, the dominant way of measuring dialysis adequacy in Kt/V and based on the clearance of urea, though the relevance of this measurement is disputed.[3]
Urea
Comparing normal to ERSD
The normal clearance of urea is approximately 100 ml/min. A patient getting a conventional hemodialysis treatment, without remaining residual function, has a urea clearance of 10-15 ml/min.[citation needed]
References
- ^ Mehta, Ankit N.; Fenves, Andrew Z. (2010). "Hemodialysis Adequacy: A Review". Dialysis & Transplantation. 39 (1): 20–22. doi:10.1002/dat.20392.
- ^ Jones, Clare B.; Bargman, Joanne M. (2018). "Should we look beyond Kt / V urea in assessing dialysis adequacy?". Seminars in Dialysis. 31 (4): 420–429. doi:10.1111/sdi.12684.
- ^ Ross Morton, A.; Singer, Michael A. (2007-01-22). "The Problem with Kt/V: Dialysis Dose should be Normalized to Metabolic Rate not Volume: PROBLEM WITH KT/V". Seminars in Dialysis. 20 (1): 12–15. doi:10.1111/j.1525-139X.2007.00232.x.
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Physiology of the kidneys and acid–base physiology
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| Reabsorption |
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| Fluid balance | |
| Acid–base balance |
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