Climbazole

IdentifiersCAS NumberPubChem CIDChemSpiderUNIIChEBIChEMBLCompTox Dashboard (EPA)ECHA InfoCard100.048.870 Chemical and physical dataFormulaC₁₅H₁₇ClN₂O₂Molar mass292.76 g·mol⁻¹3D model (JSmol)ChiralityRacemic mixture ^NY (what is this?)  (verify)

Climbazole is a topical antifungal agent commonly used in the treatment of human fungal skin infections such as dandruff, seborrhoeic dermatitis and eczema.^[2] Climbazole has shown a high in vitro and in vivo efficacy against Malassezia spp. that appear to play an important role in the pathogenesis of dandruff.^[2] Its chemical structure and properties are similar to other azole fungicides such as ketoconazole, clotrimazole and miconazole.

Indications and formulations

It is most commonly found as an active ingredient in OTC anti-dandruff and anti-fungal products, including shampoos, lotions and conditioners. It may be accompanied by other active ingredients such as zinc pyrithione or triclosan.^{[citation needed]}

Side effects

May cause localized irritation of the skin with symptoms including redness, rashes and itching.^{[citation needed]}

References