COQ4

Protein-coding gene in humans
COQ4
Identifiers
AliasesCOQ4, CGI-92, COQ10D7, coenzyme Q4
External IDsOMIM: 612898; MGI: 1098826; HomoloGene: 68641; GeneCards: COQ4; OMA:COQ4 - orthologs
Gene location (Human)
Chromosome 9 (human)
Chr.Chromosome 9 (human)[1]
Chromosome 9 (human)
Genomic location for COQ4
Genomic location for COQ4
Band9q34.11Start128,322,544 bp[1]
End128,334,072 bp[1]
Gene location (Mouse)
Chromosome 2 (mouse)
Chr.Chromosome 2 (mouse)[2]
Chromosome 2 (mouse)
Genomic location for COQ4
Genomic location for COQ4
Band2 B|2 20.62 cMStart29,677,505 bp[2]
End29,687,947 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • right uterine tube

  • olfactory zone of nasal mucosa

  • anterior pituitary

  • right lobe of thyroid gland

  • left lobe of thyroid gland

  • body of pancreas

  • mucosa of transverse colon

  • right adrenal cortex

  • skin of leg

  • skin of abdomen
Top expressed in
  • spermatocyte

  • spermatid

  • proximal tubule

  • seminiferous tubule

  • condyle

  • fossa

  • lip

  • duodenum

  • external carotid artery

  • internal carotid artery
More reference expression data
BioGPS
n/a
Gene ontology
Molecular function
  • protein binding
Cellular component
  • membrane
  • mitochondrion
  • mitochondrial inner membrane
  • protein-containing complex
  • extrinsic component of mitochondrial inner membrane
Biological process
  • ubiquinone biosynthetic process
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

51117

227683

Ensembl

ENSG00000167113

ENSMUSG00000026798

UniProt

Q9Y3A0

Q8BGB8

RefSeq (mRNA)

NM_001305942
NM_016035

NM_178693

RefSeq (protein)

NP_001292871
NP_057119

NP_848808

Location (UCSC)Chr 9: 128.32 – 128.33 MbChr 2: 29.68 – 29.69 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial is a protein that in humans is encoded by the COQ4 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000167113 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000026798 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Belogrudov GI, Lee PT, Jonassen T, Hsu AY, Gin P, Clarke CF (Jul 2001). "Yeast COQ4 encodes a mitochondrial protein required for coenzyme Q synthesis". Arch Biochem Biophys. 392 (1): 48–58. doi:10.1006/abbi.2001.2448. PMID 11469793.
  6. ^ "Entrez Gene: COQ4 coenzyme Q4 homolog (S. cerevisiae)".

External links

Further reading

  • Mehrle A, Rosenfelder H, Schupp I, et al. (2006). "The LIFEdb database in 2006". Nucleic Acids Res. 34 (Database issue): D415–8. doi:10.1093/nar/gkj139. PMC 1347501. PMID 16381901.
  • Wiemann S, Arlt D, Huber W, et al. (2004). "From ORFeome to biology: a functional genomics pipeline". Genome Res. 14 (10B): 2136–44. doi:10.1101/gr.2576704. PMC 528930. PMID 15489336.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing". EMBO Rep. 1 (3): 287–92. doi:10.1093/embo-reports/kvd058. PMC 1083732. PMID 11256614.
  • Hartley JL, Temple GF, Brasch MA (2001). "DNA cloning using in vitro site-specific recombination". Genome Res. 10 (11): 1788–95. doi:10.1101/gr.143000. PMC 310948. PMID 11076863.
  • Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876. PMID 10810093.


  • v
  • t
  • e